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HS Code |
189119 |
| Chemical Name | Benzyl Chloroformate |
| Cas Number | 501-53-1 |
| Molecular Formula | C8H7ClO2 |
| Molar Mass | 170.60 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Density | 1.21 g/cm³ |
| Boiling Point | 195-197 °C |
| Melting Point | -39 °C |
| Refractive Index | 1.535 |
| Solubility In Water | Decomposes |
| Vapor Pressure | 0.7 mmHg (20 °C) |
| Flash Point | 87 °C (closed cup) |
| Odor | Pungent, sweet |
| Storage Temperature | Below 30 °C |
| Un Number | 2618 |
As an accredited Benzyl Chloroformate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Benzyl Chloroformate, 500 mL, is supplied in an amber glass bottle with a secure screw cap and hazard labeling. |
| Container Loading (20′ FCL) | 20′ FCL: Benzyl Chloroformate is packed in 250 kg HDPE drums, totaling 80 drums per container, net weight 20 metric tons. |
| Shipping | Benzyl Chloroformate should be shipped as a hazardous material, complying with all relevant transport regulations. It must be packed in tightly sealed containers, protected from moisture and physical damage, and clearly labeled. Use secondary containment, and keep away from incompatible substances. Only trained personnel should handle and transport this chemical. |
| Storage | Benzyl Chloroformate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong bases, acids, and oxidizing agents. Protect it from moisture and direct sunlight. Store under an inert atmosphere, such as nitrogen, if possible, and ensure proper labeling. Keep away from heat sources and ignition points. |
| Shelf Life | Benzyl Chloroformate typically has a shelf life of 12–24 months when stored tightly sealed in a cool, dry, and dark place. |
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Purity 99%: Benzyl Chloroformate with a purity of 99% is used in peptide synthesis, where it ensures high coupling efficiency and minimal side reactions. Stability Temperature 25°C: Benzyl Chloroformate with a stability temperature of 25°C is used in laboratory storage applications, where it maintains structural integrity and prevents decomposition. Molecular Weight 170.6 g/mol: Benzyl Chloroformate with a molecular weight of 170.6 g/mol is used in pharmaceutical intermediate production, where it allows for precise stoichiometric calculations. Melting Point -39°C: Benzyl Chloroformate with a melting point of -39°C is used in chemical process engineering, where it enables convenient low-temperature handling and storage. Density 1.18 g/cm³: Benzyl Chloroformate with a density of 1.18 g/cm³ is used in industrial scale-up reactions, where it facilitates accurate volumetric measurements and mixing. Water Content ≤0.1%: Benzyl Chloroformate with water content ≤0.1% is used in moisture-sensitive synthesis, where it prevents hydrolysis and ensures product purity. Colorless Liquid: Benzyl Chloroformate as a colorless liquid is used in analytical chemistry applications, where it allows easy monitoring of reaction progress visually. Boiling Point 195°C: Benzyl Chloroformate with a boiling point of 195°C is used in distillation processes, where it permits efficient separation and purification. |
Competitive Benzyl Chloroformate prices that fit your budget—flexible terms and customized quotes for every order.
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Our decades in the chemical manufacturing field have shown us where the real value lies within specialty production. Benzyl Chloroformate, which carries the chemical formula C8H7ClO2, comes into play as a true workhorse in laboratories and plants that demand robust intermediates and safe, consistent outputs. Since the 1970s, its role in pharmaceutical, agrochemical, and fine chemical syntheses has only grown.
We manufacture Benzyl Chloroformate in both bulk and bespoke grades. Customers working at scale seek high purity above 99%, transparent or near-colorless liquid, and granular control over water and acid content. Our strengths as a direct producer shine through this process. We blend experienced operational oversight with modern analytical methods—think titration, GC-MS, NMR, and precise drying techniques. This keeps both material and process on-target so nobody faces last-minute surprises downstream.
Our engineers have noticed buyers sometimes focus only on purity specs, chasing an extra decimal point. Yet experience shows that real success with Benzyl Chloroformate often comes from eliminating batch-to-batch variation and minimizing byproduct formation. We’ve responded to these needs by investing in continuous-flow technology, tight temperature control, and stepwise dosing systems. By dialling in reaction parameters, unwanted side-products such as benzyl alcohol or phosgene residues remain consistently below trace levels.
Many older producers use open-batch methods that risk oxidation, variable coloring, or residual acidity. These defects may not register in a purity report, but they show up quickly during sensitive carbamoylation steps. We’ve responded to questions from process chemists who ‘do everything right’ only to face odd impurities or reversed selectivity. From firsthand batch records, we see how steady heat cycling and inert atmospheres clear up consistency problems—the sort of details overlooked by traders or those pushing only desk specs.
Benzyl Chloroformate doesn’t need fancy attachments or stabilizers to do its job—what matters is clarity, density, and a predictable reactivity profile. Our product leaves the plant as a transparent to slightly yellow liquid, with a minimum assay of 99.0% (typically reaching up to 99.5%), and a specific gravity tightly held between 1.18–1.20 at 20°C. This ensures downstream workflows like carbamate protection proceed without lengthy screening or reworking.
Years on the production floor reinforce this lesson: moisture, residual hydrochloric acid, or dissolved metals are common headache sources in poorly-controlled lots. We keep water content below 0.1% with molecular sieves and immediate, sealed storage. Each batch clears free acid checks not by default but due to careful post-synthesis neutralization and filtration. Consistency through these details let our partners avoid resin fouling, unwanted hydrolysis, and sluggish reaction times—small errors grow quickly at scale, so control from start to drum pays off.
Customers in pharmaceutical R&D use Benzyl Chloroformate in peptide synthesis for creating N-benzyloxycarbonyl (Cbz) protecting groups. Over the years, we’ve supported teams working on everything from antiviral compounds to custom peptide libraries. Chemists appreciate that our Cbz-Cl does not introduce interfering side compounds, which helps yield clean products that fit regulatory demands. For isolation and scale-up teams, this kind of reliability has direct impact on yield, time, and purity—a bad batch can cost weeks and spike compliance risks.
Agrochemical manufacturers often use Benzyl Chloroformate for urea and carbamate construction. A clean, controlled reaction profile means higher conversion and fewer steps between raw feedstock and finished active ingredient. Less time troubleshooting raw material quirks frees project teams to focus on regulatory registration, formulation, and market deadlines. Many academic partnerships also count on trusted Benzyl Chloroformate for synthetic methodology research, such as developing new coupling techniques or exploring fresh step-economies in organic transformations.
From experience, Benzyl Chloroformate stands apart from methyl or ethyl analogues due to its favorable leaving group ability and ease of handling. The benzyl group brings both increased reactivity and convenient deprotection via mild hydrogenation. Compared to diphosgene or phosgene itself, risks drop sharply—our product can be shipped and stored under regular chemical site conditions, avoiding the acute toxicity and specialized piping headaches tied to gaseous phosgene.
Some customers consider alternative protecting agents like Boc (tert-butyloxycarbonyl) or Fmoc (fluorenylmethyloxycarbonyl) for peptide work. These have their place, especially in solid-phase synthesis. Still, in solution-phase or for base-sensitive substrates, Benzyl Chloroformate offers more predictable cleavage and less harsh removal conditions. In real-world use, our Benzyl Chloroformate saves time in process optimization and downstream purification stages.
Working as a manufacturer, not a trader, brings direct oversight from sourcing to packaging. Each barrel and container is traced back through detailed batch records and quality audits. We buy only vetted benzyl alcohol and phosgene alternatives, follow strict environmental protocols, and use sealed filling operations. In the event that a customer reports an issue, root-cause analysis happens rapidly—much faster than through a tangled supply network.
From our own safety audits, we know Benzyl Chloroformate should never be handled lightly. We supply clear, practical storage instructions, with reinforced drums and tamper-evidence as a practical measure against accidental leaks or contamination. All transport follows the latest regulatory updates, and our field specialists work directly with partners facing unique logistic or compliance hurdles. Safety data sits built-in to every label and shipment file.
Meeting regulatory and industry benchmarks means more than paperwork—it means delivering material that answers real chemists’ needs. We analyze every lot for residual solvents, acid content, and even color in the APHA scale, not because a certificate demands it, but because we’ve seen real-world failures from batches ignored by less diligent firms. We calibrate equipment weekly using traceable standards, and keep working with our best customers to evolve specs as processing trends shift.
The result? Fewer customer complaints, higher downstream yields, and a reputation for material that doesn’t “just pass”—it delivers. Years of feedback from contract manufacturers, pharma labs, and agchem plants make us adjust specs: trace metals, halide screening, reaction history documentation, and even surfactant-free filling come from experience, not slogans. We’ve managed claims down to single occurrences per thousand drums shipped by following this approach.
Chemists and engineers often turn to us for troubleshooting. Someone might run into cloudiness, slow reaction, or unexpected byproducts when switching suppliers—even if the paper specs look identical. Because we built our Benzyl Chloroformate production process from the ground up, we help partners understand reaction kinetics, storage sensitivities, or even how small shifts in pH can steer selectivity. We do not just ship material; we help optimize carbamate protection, scale-up strategies, and post-synthesis handling.
Practical solutions come from facing real production headaches. Water intrusion before fullness testing, for example, led us to overhaul our drum capping and inner seal design. A pattern of yellowing in hot weather shipments drove us to redesign chilled truck loading, now standard for distant or warm-region customers. Each challenge leaves a mark on the way we work, and the adjustments show in consistent customer retention and cleaner, faster production for our partners.
Sustainability and regulatory pressures have changed the way Benzyl Chloroformate gets made, stored, and shipped. We operate under local and international standards, following REACH, TSCA, and relevant safety and emission rules. Our waste streams go through two-step neutralization and carbon treatment, ensuring minimal environmental impact. We have invested in emissions scrubbing and vapor recovery for phosgene handling—eliminating the risk of exposure and minimizing waste.
Customers often ask about compliance support for audits or registrations. By maintaining full batch traceability and giving clients access to full analytical documentation, we make regulatory filings straightforward. Inspections find us prepared, as do third-party auditors. Over time, this track record has helped our customers avoid delays when submitting product dossiers or launching new projects in restricted regions.
We believe progress in chemical manufacturing comes from listening, adapting, and applying hard-won lessons. Each iteration of our Benzyl Chloroformate production has followed from specific requests—more predictable reactivity, stronger drums, sealed valve outlets for bulk users. Even choices such as on-site safety drills or deeper batch analytics stem from both regulatory change and direct customer feedback.
Our operators have fielded questions at 3am, walked customers through raw material challenges, and retrofitted storage protocols after rare but instructive incidents. This cycle of open communication and responsiveness—rather than relying on buzzwords or templated claims—keeps quality rising. Problems that sometimes look small grow big if ignored; we work to catch them early by staying close to the plant floor and the process laboratory.
As a manufacturer, we see where Benzyl Chloroformate really stands out. Quality built into every kg, not just signed off by a certificate. Systematic removal of trace water, acid, and oxidants. In-house logistics solutions that match the scale and risk profile of shipments, whether moving drums across the factory or containers across continents. Batch-specific support—someone who knows where each lot of feedstock, catalyst, and additive came from on a given production day.
This approach may take more effort and resources, but it brings proven safety, traceability, and efficiency. For our customers, it reduces reaction troubleshooting, downtime, and material waste. For us, it builds accountability—customers know whom to call, what they are getting, and how their feedback loops back to make the next delivery better.
We treat Benzyl Chloroformate not just as a product, but as an ongoing commitment to partners and their processes. By engaging customers in direct conversation, adapting to their protocol shifts, and openly discussing risks and improvements, we have built relationships that last over years, not transactions that end after a shipment. This gives both sides room to innovate—whether in formulation, logistics, or regulatory filings.
From a manufacturer’s perspective, trust grows from solving real problems, showing up when something does not go as planned, and staying current with operational best practices. Every drum or bulk container of Benzyl Chloroformate leaving our plant reflects this ethic, as seen in stable reactivity profiles, clear documentation, and open lines of support.
The chemical industry faces tighter emission norms, growing safety pressures, and evolving customer needs. Direct manufacturing provides a foundation for facing these shifts. Upgrades to reaction containment, real-time process monitoring, and digitalized batch tracking keep our operations compliant and competitive. Customers with new green chemistry targets or advanced purification demands find us prepared to engage—not just promise, but test and implement changes that match industry direction.
Some sectors now ask for renewable feedstocks or closed-loop waste handling. Our R&D team explores these pathways, trialling bio-based benzyl alcohols and post-process solvent recovery, looking to extend Benzyl Chloroformate’s legacy into more sustainable territory. Practicality guides each step; we focus on changes that actually benefit customers in lab, pilot, and plant runs.
Those buying Benzyl Chloroformate from a true manufacturer see benefits beyond material specs. Immediate technical support, rapid documentation turnaround, and tailored packaging solutions help avoid downtime. Unusual requirements—such as custom blend ratios, low-temperature packaging, or documentation for specialized audits—fit into our workflows, not as an afterthought but as regular practice.
Repeat customers know their feedback triggers new investments, process tweaks, and follow-through. We invest in our workforce so each handoff from production to QC to logistics matches the standards we claim. No pack gets loaded or shipped until checks confirm tamper-evidence, right labeling, and chemical compliance—all handled by people experienced in the hazards, quirks, and final applications of Benzyl Chloroformate.
Benzyl Chloroformate continues to be more than a line-item commodity for us. Decades refining the process and building direct relationships with end-users shape its quality, reliability, and reputation. Feedback from critical process failures or regulatory hurdles doesn’t just get acknowledged—it leads to change in formulation, handling, and support. In our experience, this makes all the difference; a material that behaves the way it should, every time, moves projects further, keeps teams safe, and builds trust between customer and manufacturer.
Those who work with us know the value comes through not only in high purity, low impurity content, and reliable documentation, but in a willingness to stand behind every kilogram shipped. Benzyl Chloroformate may carry risk and complexity, but handled with process expertise and responsive support, it drives productivity and innovation across fields. This commitment has made our partnership with customers more than a sale—it is a shared investment in each batch, each process, and each new idea.